Why Cystoliberin®

About
//cystoliberin.com/wp-content/uploads/2022/09/cystoliberin_125ml_30cp_CRP_2022-08.png
WHY

CYSTOLIBERIN®?

Its effectiveness is clinically proven;it helps the patient and doctor in lower urinary tract infections with its active components, which can be used in the treatment process or for protective purposes.
You can safely use.
About

Pathogenesis And Mechanism Of Action

D Mannoz, PAC

Prevention of adhesion to the mucosa
Bacteria reach the urinary system ascending, hematogenous or lymphatic way.
It clings to the bladder mucosa with adhesion and begins to multiply.

Arbutin

Prevent colonization
The bacteria that grows colony
and infect.

patojenez ve etki
Terphenes, Flavonoids, Pinens

Anti-inflammatuar, analgesic, diuretic effect
Infecting bacterial colonization causes inflammation, pain or burning.

  1. Andrea Occhipinti et al, Prevention of Urinary Tract Infection with Oximacro®, A Cranberry Extract with a High Content of A-Type Proanthocyanidins: A Pre-Clinical Double-Blind Controlled Study, Urology journal, 2016.
    2. L Domenici, M Monti, C Bracchi, M Giorgini, V Colagiovanni, L Muzii, P Benedetti Panici; D-mannose: a promising support for acute urinary tract infections in women. A pilot study;  2016 Jul;20(13):2920-5.
    3. E K Michaels, J S Chmiel, B J Plotkin, A J Schaeffer; Effect of D-mannose and D-glucose on Escherichia coli bacteriuria in rats; 1983;11(2):97-102.  doi:.1007/BF00256954.
    4. Gernot Schindler, MD, Ulrich Patzak, PhD, Benno Brinkhaus, MD, Alexander von Nieciecki, PhD, Jörg Wittig, PhD, Nils Krähmer, Ingmar Glöckl, PhD, and Markus Veit, PhD; Urinary Excretion and Metabolism of Arbutin after Oral Administration of Arctostaphylos uvae ursi Extract as Film-Coated Tablets and Aqueous Solution in Healthy Humans; J Clin Pharmacol 2002;42:920-927.
    5. Tommaso Cai et al, The Ecacy of Umbelliferone, Arbutin, and N-Acetylcysteine to Prevent Microbial Colonization and Biolm Development on Urinary Catheter Surface, Journal of Pathogens Volume 2016, Article ID 1590952, 6 pages; doi:10.1155/2016/1590952.
    6. Makson G B de Oliveira 1, Rosemarie B Marques, Michele F de Santana, Amanda B D Santos, Fabíola A Brito, Emiliano O Barreto, Damião P De Sousa, Fernanda R C Almeida, Daniel Badauê-Passos Jr, Angelo R Antoniolli, Lucindo J Quintans-Júnior;; α-terpineol reduces mechanical hypernociception and inflammatory response; . 2012 Aug;111(2):120-5. doi: 10.1111/j.1742-7843.2012.00875.x. Epub 2012 Apr 11.
    7. Xiangquan Zeng 1,  Yu Xi 1,  Weibo Jiang 1 Protective roles of flavonoids and flavonoid-rich plant extracts against urolithiasis: A review ; 2019; 59 (13): 2125-2135. doi: 10.1080 /10408398.2018.1439880. Epub 2018 31 May.
    8. Bahare Salehi, Shashi Upadhyay, Ilkay Erdogan Orhan, Arun Kumar Jugran, Sumali L D Jayaweera, Daniel A Dias, Farukh Sharopov, Yasaman Taheri, Natália Martins, Navid Baghalpour, William C Cho, Javad Sharifi-Rad; Therapeutic Potential of α- and β-Pinene: A Miracle Gift of Nature; . 2019 Nov 14;9(11):738. doi: 10.3390/biom9110738.
Features
custom-upload
Safe

Safe for gut microbiota,
beneficial bacteria and vaginal flora

custom-upload
Proven

Its effectiveness in lower urinary tract infection
has been clinically proven

custom-upload
Ease Of Use

It provides easy absorption with its suspension form.
It is suitable for use by both adults and children.

custom-upload
Combined Formulation

It is the first combined formulation in Turkey. It provides fast and effective support for lower urinary tract infection with its multi-component technology consisting of 6 different ingredients.

custom-upload
Is Standardized

It has standardized contents. The amount of active ingredient is determined for each dose.

custom-upload
Does Not Cause Side Effects

It is suitable for long-term use. It does not cause antibiotic resistance.

Contact
C/ Joaquim Costa 18, 1st floor, 08390 Montgat (Barcelona), SPAIN

social@setonda.com

+34 93 469 22 66